Aloe Vera

Aloe VeraAloe Vera’s botanical name is Aloe barbadensis miller and it is a shrubby plant that grows in the dry regions of various continents including Asia, Europe and the Americas. Several ancient cultures have used Aloe Vera for health benefits such as ancient Greeks, Egyptians, Indians, and Chinese. They all used it to manage health conditions so successfully that the Ancient Egyptians called Aloe Vera “the plant of immortality”.1

Aloe Vera has numerous well-documented health benefits due to its content of various phytocompounds. It is rich in Vitamins A, C, and E, antioxidants, enzymes, minerals, monosaccharides, polysaccharides, anthraquinones (providing laxative and antimicrobial properties), fatty acids, hormones, and amino acids.1

Aloe Vera is available in numerous forms, including powder, capsules, liquids, mouthwashes, topical ointments, and cosmetics. Below are some of the health benefits and reasons people use Aloe Vera.

Health Benefits of Aloe Vera

  • Immune Booster

    Aloe Vera is an immunostimulant. Various experimental studies show that Aloe Vera may influence human immunity in numerous ways which may be due to its content of antioxidants, anti-inflammatory enzymes, micronutrients, and so on. It seems that Aloe Vera extract may have a direct effect on human immunity, however, the underlying mechanism is not yet properly understood by researchers. Nonetheless, the ability of Aloe Vera to boost nonspecific immune responses is confirmed by experimental studies.2,3

  • Anti-Inflammatory

    Aloe Vera may also help suppress inflammation and therefore boost various healing processes. This is thought to be due to the direct anti-inflammatory action of some of the enzymes contained in Aloe Vera. Studies also show that the use of Aloe Vera can suppress the induction of pro-inflammatory cytokine in response to various microbial infections.4

  • Antioxidant

    There are numerous compounds in Aloe Vera, with antioxidant capacity, including Vitamin E, Vitamin C and various phenolic compounds. Studies show that aloesin derivatives in the plant also have potent free radical scavenging capabilities and therefore, the use of Aloe Vera and it’s extract can help in numerous health conditions.5

  • Antimicrobial

    Researchers have isolated various Aloe proteins with potent antimicrobial activity. Therefore, Aloe Vera can suppress multiple gram-positive and gram-negative pathogens and it has also been found to possess antifungal activity.6

  • Prevent Dental Plaque

    Aloe Vera also has a role as a natural mouth wash due to its anti-inflammatory and antimicrobial properties. Studies in humans have confirmed that regular use of Aloe Vera can help prevent dental plaque.7
  • Manage Skin Issues and Aid Wound Healing

    Aloe Vera has numerous beneficial effects on skin health. The use of Aloe Vera can help to prevent sunburn, fight infections, help with autoimmune conditions (like psoriasis), eczema, fungal infections and bacterial infections. The use of Aloe Vera may even help with certain viral skin conditions like human papillomavirus. Therefore, it is no surprise that Aloe Vera is commonly included in various topical applications.8
  • Manage Constipation

    Studies show that Aloe Vera is a potent natural laxative. It seems to be comparable to some of the over-the-counter medications, in managing constipation, and so due to its excellent safety profile, it may be a particularly good alternative for older adults or those living with chronic constipation.9
  • Lowers Blood Sugar Levels

    Aloe Vera may not be the most potent anti-diabetes remedy; nonetheless, studies show that use of Aloe Vera can help those living with type 2 diabetes.10

Side Effects of Aloe Vera

Aloe Vera is relatively safe for short-term or intermittent use and rarely causes any side effects. However, its prolonged use may cause some adverse effects. Frequent topical use may cause allergic reactions and photosensitivity. Oral use may cause abdominal cramps and diarrhea. Its prolonged use at higher dosages may be toxic for some internal organs, like the liver and kidneys, and pregnant and lactating women should avoid its use internally. It should be used cautiously with other medications due to the possibilities of interactions.1,11

Properties

  • Adaptogen2,3,5
  • Allergies2,3
  • Anti-Bacterial6
  • Anti-Fungal6
  • Anti-Inflammatory8
  • Antibiotic6
  • Antimicrobial6
  • Antioxidant5
  • Antiseptic6
  • Asthma2,5
  • Constipation9
  • Demulcent9
  • Diabetes / Blood Sugar10
  • Digestive Function9
  • Digestive Restoration9
  • Encourages Healing8
  • High/Good Levels of Phytochemicals / Phytocompounds1
  • High/Good Levels of Vitamin A1
  • High/Good Levels of Vitamin C1
  • High/Good Levels of Vitamin E1
  • Immune Booster2,3
  • Laxative9
  • Oral Health7
  • Skin Issues8
  • Ulcer Support8
  • Wound Healing8

References

  1. Surjushe A, Vasani R, Saple DG. ALOE VERA: A SHORT REVIEW. Indian J Dermatol. 2008;53(4):163-166. doi:10.4103/0019-5154.44785
  2. Mehrabi Z, Firouzbakhsh F, Rahimi-Mianji G, Paknejad H. Immunostimulatory effect of Aloe vera (Aloe barbadensis) on non-specific immune response, immune gene expression, and experimental challenge with Saprolegnia parasitica in rainbow trout (Oncorhynchus mykiss). Aquaculture. 2019;503:330-338. doi:10.1016/j.aquaculture.2019.01.025
  3. Mojtaba A, Mahdi RM, Masoud G, Rahim P, Mehrzad M, Mohammad RJ. EFFECTS OF DIETARY ALOE VERA ON SOME SPECIFIC AND NONSPECIFIC IMMUNITY IN THE COMMON CARP (CYPRINUS CARPIO). 2010;4(3):189-195.
  4. Habeeb F, Stables G, Bradbury F, et al. The inner gel component of Aloe vera suppresses bacterial-induced pro-inflammatory cytokines from human immune cells. Methods. 2007;42(4):388-393. doi:10.1016/j.ymeth.2007.03.005
  5. Yagi A, Kabash A, Okamura N, Haraguchi H, Moustafa SM, Khalifa TI. Antioxidant, Free Radical Scavenging and Anti-Inflammatory Effects of Aloesin Derivatives in Aloe vera. Planta Med. 2002;68(11):957-960. doi:10.1055/s-2002-35666
  6. Radha MH, Laxmipriya NP. Evaluation of biological properties and clinical effectiveness of Aloe vera: A systematic review. Journal of Traditional and Complementary Medicine. 2015;5(1):21-26. doi:10.1016/j.jtcme.2014.10.006
  7. Kumar GR, Devanand G, John BD, Ankit Y, Khursheed O, Sumit M. Preliminary Antiplaque Efficacy of Aloe Vera Mouthwash on 4 Day Plaque Re -Growth Model: Randomized Control Trial. Ethiopian Journal of Health Sciences. 2014;24(2):139-144. doi:10.4314/ejhs.v24i2.6
  8. A F, Mr N. Aloe vera in dermatology: a brief review. G Ital Dermatol Venereol. 2009;144(1):85-91.
  9. Ashafa T, Sunmonu T, Abass A, Ogbe A. Laxative potential of the ethanolic leaf extract of Aloe vera (L.) Burm. f. in Wistar rats with loperamide-induced constipation. Journal of natural pharmaceuticals. 2011;2. doi:10.4103/2229-5119.86268
  10. Okyar A, Can A, Akev N, Baktir G, Sütlüpinar N. Effect of Aloe vera leaves on blood glucose level in type I and type II diabetic rat models. Phytotherapy Research. 2001;15(2):157-161. doi:https://doi.org/10.1002/ptr.719
  11. BOUDREAU MD, BELAND FA. An Evaluation of the Biological and Toxicological Properties of Aloe Barbadensis (Miller), Aloe Vera. Journal of Environmental Science and Health, Part C. 2006;24(1):103-154. doi:10.1080/10590500600614303